Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 3/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634798 | 0.94 | PIM1 (0.48) | PIM1MEN1KMT2APAICSGPR6 | |
| SCHEMBL13634676 | 0.87 | GPR6 (0.42) | PIM1CYP2C9CYP2C19PAICSGPR6 | |
| SCHEMBL13634801 | 0.86 | CNR1 (0.46) | PIM1CYP2C9CYP2C19PAICSGPR6 | |
| SCHEMBL13634596 | 0.86 | GPR6 (0.38) | PIM1CYP2C19PAICSGPR6ALDH1A1 | |
| SCHEMBL13634635 | 0.86 | PIM1 (0.45) | PIM1GPR6ALDH1A1 | |
| SCHEMBL13638871 | 0.85 | TGFBR1 (0.36) | PIM1CYP2C9CYP2C19PAICSGPR6 | |
| SCHEMBL13634580 | 0.85 | GPR6 (0.36) | PAICSGPR6 | |
| SCHEMBL13634512 | 0.85 | SCD (0.39) | PIM1CYP2C9CYP2C19PAICSGPR6 | |
| SCHEMBL13634508 | 0.85 | ALDH1A1 (0.41) | PAICSGPR6ALDH1A1 | |
| SCHEMBL13634571 | 0.85 | GPR6 (0.34) | PIM1PAICSGPR6CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |