Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638813 | 0.93 | PDCD1 (0.39) | MCHR1UTS2RGPR6KDM4EACKR3 | |
| SCHEMBL13634814 | 0.90 | MCHR1 (0.39) | MCHR1UTS2RF10LMNASMN1; SMN2 | |
| SCHEMBL13634779 | 0.89 | MCHR1 (0.43) | MCHR1UTS2RGPR6ACKR3MAPK1 | |
| SCHEMBL13634816 | 0.86 | MCHR1 (0.38) | MCHR1F10LMNASMN1; SMN2MEN1 | |
| SCHEMBL13270762 | 0.83 | S1PR1 (0.40) | MCHR1GPR6F10LMNASMN1; SMN2 | |
| SCHEMBL13638815 | 0.82 | MCHR1 (0.43) | MCHR1UTS2RGPR6 | |
| SCHEMBL13270419 | 0.81 | F10 (0.40) | MCHR1F10LMNASMN1; SMN2MAPK1 | |
| SCHEMBL13634704 | 0.81 | MCHR1 (0.38) | MCHR1UTS2RGPR6SLC2A1F10 | |
| SCHEMBL13634861 | 0.81 | MCHR1 (0.38) | MCHR1UTS2RGPR6SLC2A1F10 | |
| SCHEMBL13638822 | 0.80 | MCHR1 (0.38) | MCHR1UTS2RSLC2A1ACKR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |