Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638815 | 0.94 | MCHR1 (0.43) | MCHR1UTS2RIRAK4GPR6 | |
| SCHEMBL13634616 | 0.89 | MCHR1 (0.38) | MCHR1UTS2RACKR3GPR6MAPK1 | |
| SCHEMBL13634601 | 0.89 | MCHR1 (0.43) | MCHR1UTS2RIRAK4ACKR3GPR6 | |
| SCHEMBL13270419 | 0.85 | F10 (0.40) | MCHR1IRAK4MAPK1 | |
| SCHEMBL13270762 | 0.84 | S1PR1 (0.40) | MCHR1IRAK4GPR6MAPK1 | |
| SCHEMBL13638812 | 0.84 | GPR6 (0.39) | MCHR1IRAK4GPR6 | |
| SCHEMBL13634670 | 0.84 | PARP1 (0.38) | MCHR1IRAK4GPR6 | |
| SCHEMBL13634814 | 0.83 | MCHR1 (0.39) | MCHR1UTS2RIRAK4MAPK1 | |
| SCHEMBL13638813 | 0.82 | PDCD1 (0.39) | MCHR1UTS2RACKR3GPR6 | |
| SCHEMBL13634816 | 0.82 | MCHR1 (0.38) | MCHR1IRAK4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |