Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638933 | 0.94 | MCHR1 (0.39) | PARP1TNK1MCHR1GLSF10 | |
| SCHEMBL13634818 | 0.94 | MCHR1 (0.41) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634687 | 0.92 | GPR6 (0.38) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634618 | 0.92 | GPR6 (0.38) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634705 | 0.92 | GPR6 (0.39) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634885 | 0.91 | GLS (0.41) | MCHR1GLSGPR6CYP2C9 | |
| SCHEMBL13634704 | 0.91 | MCHR1 (0.38) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634522 | 0.91 | GPR6 (0.39) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634861 | 0.91 | MCHR1 (0.38) | PARP1TNK1MCHR1GLSGPR6 | |
| SCHEMBL13634583 | 0.91 | GLS (0.39) | PARP1TNK1MCHR1GLSGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |