Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638943 | 0.94 | IRAK4 (0.39) | IRAK4HDAC1KCNH2HDAC3HDAC4 | |
| SCHEMBL13634718 | 0.89 | IRAK4 (0.47) | IRAK4L3MBTL1 | |
| SCHEMBL13634799 | 0.86 | IRAK4 (0.41) | IRAK4L3MBTL1 | |
| SCHEMBL13634555 | 0.85 | IRAK4 (0.38) | IRAK4 | |
| SCHEMBL13634737 | 0.84 | IRAK4 (0.40) | IRAK4 | |
| SCHEMBL13634549 | 0.83 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL13634866 | 0.83 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL13634912 | 0.83 | IRAK4 (0.38) | IRAK4 | |
| SCHEMBL13638768 | 0.82 | IRAK4 (0.46) | IRAK4L3MBTL1 | |
| SCHEMBL13634556 | 0.82 | IRAK4 (0.37) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |