Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634524 | 0.93 | IRAK4 (0.37) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13638993 | 0.93 | IRAK4 (0.38) | IRAK4JAK2JAK1GRM2DNM1L | |
| SCHEMBL13634549 | 0.93 | IRAK4 (0.39) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634799 | 0.92 | IRAK4 (0.41) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634556 | 0.91 | IRAK4 (0.37) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634718 | 0.91 | IRAK4 (0.47) | IRAK4KMT2A | |
| SCHEMBL13634836 | 0.91 | IRAK4 (0.37) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634764 | 0.91 | IRAK4 (0.37) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634737 | 0.90 | IRAK4 (0.40) | IRAK4JAK2JAK1GRM2KMT2A | |
| SCHEMBL13634661 | 0.89 | S1PR1 (0.42) | IRAK4KMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |