Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.32 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.32 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.32 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634877 | 1.00 | PDCD1 (0.35) | PDCD1CD274PIM1SCDSCD5 | |
| SCHEMBL13638780 | 0.93 | PDCD1 (0.36) | PDCD1CD274SCDSCD5METTL3 | |
| SCHEMBL13634925 | 0.93 | PDCD1 (0.36) | PDCD1CD274SCDSCD5METTL3 | |
| SCHEMBL13634767 | 0.88 | SCD (0.37) | PIM1SCDSCD5GPR6CNR2 | |
| SCHEMBL13634852 | 0.87 | HDAC1 (0.36) | PIM1SCDSCD5KMT2AIRAK4 | |
| SCHEMBL13634647 | 0.87 | HDAC1 (0.36) | PIM1SCDSCD5KMT2AIRAK4 | |
| SCHEMBL13270650 | 0.87 | MAPT (0.39) | SCDSCD5KMT2AIRAK4 | |
| SCHEMBL13634847 | 0.86 | IRAK4 (0.37) | SCDSCD5KMT2AIRAK4 | |
| SCHEMBL13634846 | 0.86 | IRAK4 (0.37) | SCDSCD5KMT2AIRAK4 | |
| SCHEMBL13634927 | 0.86 | CNR2 (0.36) | PIM1SCDSCD5GPR6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |