Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 5/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634767 | 0.95 | SCD (0.37) | CNR2SCDSCD5PIM1PIN1 | |
| SCHEMBL13634578 | 0.92 | GLS (0.39) | SCDSCD5PIM1PIN1PIM3 | |
| SCHEMBL15888680 | 0.92 | PIN1 (0.36) | SCDSCD5PIM1PIN1PIM3 | |
| SCHEMBL2770287 | 0.92 | PIN1 (0.36) | SCDSCD5PIM1PIN1PIM3 | |
| SCHEMBL13638833 | 0.91 | GRM2 (0.39) | CNR2SCDSCD5PIM1PIN1 | |
| SCHEMBL13634559 | 0.90 | ALDH1A1 (0.41) | — | |
| SCHEMBL13634761 | 0.88 | ABCB1 (0.39) | CNR2SCDSCD5DRD2DRD4 | |
| SCHEMBL13270769 | 0.88 | ITK (0.36) | CNR2SCDSCD5PIM1PIN1 | |
| SCHEMBL13634738 | 0.88 | GRM2 (0.35) | CNR2SCDSCD5PIM1PIN1 | |
| SCHEMBL13270650 | 0.88 | MAPT (0.39) | SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |