Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638992 | 0.95 | IRAK4 (0.39) | IRAK4OPRK1KMT2AIDH1SYK | |
| SCHEMBL13638937 | 0.92 | IRAK4 (0.38) | IRAK4OPRK1KMT2AIDH1SYK | |
| SCHEMBL13634602 | 0.89 | IDH1 (0.40) | MALT1IRAK4OPRK1KMT2AIDH1 | |
| SCHEMBL13634523 | 0.87 | IDH1 (0.38) | IRAK4OPRK1KMT2AIDH1GPR6 | |
| SCHEMBL13634783 | 0.87 | IRAK4 (0.48) | IRAK4OPRK1KMT2A | |
| SCHEMBL13638779 | 0.86 | MAP4K1 (0.39) | IDH1SYKGPR6 | |
| SCHEMBL13634650 | 0.82 | IRAK4 (0.50) | IRAK4OPRK1KMT2A | |
| SCHEMBL13638885 | 0.82 | IRAK4 (0.47) | IRAK4OPRK1KMT2AMAPK14 | |
| SCHEMBL13638818 | 0.82 | DRD4 (0.41) | KMT2A | |
| SCHEMBL13638823 | 0.82 | DRD4 (0.41) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |