Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638818 | 1.00 | DRD4 (0.41) | DRD4GRM2AXLMCHR1SIGMAR1 | |
| SCHEMBL2770473 | 0.91 | KMT2A (0.44) | MCHR1KMT2A | |
| SCHEMBL13634817 | 0.90 | DRD4 (0.45) | DRD4GRM2MCHR1SIGMAR1KMT2A | |
| SCHEMBL13634530 | 0.90 | DRD4 (0.45) | DRD4GRM2MCHR1SIGMAR1KMT2A | |
| SCHEMBL13638830 | 0.90 | DRD4 (0.42) | DRD4GRM2SIGMAR1KMT2A | |
| SCHEMBL13638937 | 0.90 | IRAK4 (0.38) | AXLKMT2A | |
| SCHEMBL13638822 | 0.89 | MCHR1 (0.38) | MCHR1KMT2APARP1TNK1 | |
| SCHEMBL13638909 | 0.89 | MCHR1 (0.38) | MCHR1PARP1TNK1 | |
| SCHEMBL13634805 | 0.89 | MCHR1 (0.38) | MCHR1PARP1TNK1 | |
| SCHEMBL13638886 | 0.89 | MCHR1 (0.38) | MCHR1KMT2APARP1TNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |