Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638761 | 0.93 | KMT2A (0.46) | IRAK4MAPTTSHRF10CHRM2 | |
| SCHEMBL13634662 | 0.90 | IRAK4 (0.47) | IRAK4MAPTTSHRF10OPRK1 | |
| SCHEMBL13164102 | 0.89 | IRAK4 (0.42) | IRAK4MAPTTSHRF10CHRM2 | |
| SCHEMBL13634710 | 0.86 | MCHR1 (0.37) | CHRM2CHRM3PARP1TNK1 | |
| SCHEMBL13634740 | 0.83 | MAPT (0.41) | IRAK4MAPTTSHRF10S1PR1 | |
| SCHEMBL13634661 | 0.83 | S1PR1 (0.42) | IRAK4MAPTTSHRF10S1PR1 | |
| SCHEMBL13270601 | 0.83 | KMT2A (0.54) | IRAK4MAPTTSHROPRK1KMT2A | |
| SCHEMBL13634718 | 0.81 | IRAK4 (0.47) | IRAK4OPRK1KMT2A | |
| SCHEMBL13634884 | 0.81 | S1PR1 (0.40) | IRAK4MAPTTSHRF10S1PR1 | |
| SCHEMBL13638819 | 0.80 | MCHR1 (0.37) | CHRM2CHRM3PARP1TNK1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |