Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772043 | 0.93 | KMT2A (0.48) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13634662 | 0.91 | IRAK4 (0.47) | MAPTTSHRF10IRAK4KMT2A | |
| SCHEMBL13634884 | 0.91 | S1PR1 (0.40) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13634866 | 0.89 | IRAK4 (0.39) | IRAK4DRD4KMT2A | |
| SCHEMBL13634886 | 0.88 | ACKR3 (0.38) | F10DRD4 | |
| SCHEMBL13634740 | 0.88 | MAPT (0.41) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13638912 | 0.85 | KMT2A (0.47) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13270650 | 0.84 | MAPT (0.39) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13634540 | 0.84 | S1PR1 (0.40) | S1PR1MAPTTSHRF10IRAK4 | |
| SCHEMBL13634573 | 0.83 | KMT2A (0.42) | IRAK4KMT2AMEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |