Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635177 | 0.85 | P2RY12 (0.57) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13635179 | 0.84 | P2RY12 (0.54) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13635099 | 0.84 | P2RY12 (0.52) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13635285 | 0.83 | P2RY12 (0.63) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL4415315 | 0.83 | P2RY12 (0.52) | P2RY12TP53KMT2AGAAMAPT | |
| SCHEMBL13635630 | 0.83 | P2RY12 (0.55) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13634873 | 0.82 | P2RY12 (0.52) | P2RY12TP53KMT2AGAAMAPT | |
| SCHEMBL4418832 | 0.82 | P2RY12 (0.54) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13635102 | 0.82 | P2RY12 (0.51) | P2RY12TP53HTR3AKMT2AGAA | |
| SCHEMBL13635629 | 0.82 | P2RY12 (0.52) | P2RY12TP53HTR3AKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1668002-B1 | 2,4-DIOXO-3-QUINAZOLINYLARYL SULFONYLUREAS | PORTOLA PHARM INC (US) | 2009-11-11 | — | — | EP | disclosed |