Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270655 | 0.94 | ACHE (0.41) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13634785 | 0.94 | MAPK1 (0.43) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13162740 | 0.92 | CHEK1 (0.39) | ACHE | |
| SCHEMBL13634734 | 0.90 | KMT2A (0.41) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13634758 | 0.90 | KMT2A (0.41) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL2772472 | 0.90 | KMT2A (0.49) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13634740 | 0.90 | MAPT (0.41) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13634851 | 0.90 | PDE4B (0.44) | KMT2AF10 | |
| SCHEMBL13270599 | 0.89 | MAPT (0.41) | ACHEIRAK4KMT2AMAPTTSHR | |
| SCHEMBL13634936 | 0.88 | IRAK4 (0.41) | IRAK4KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |