Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 14/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | CAMK4 | Q16566 | 1/20 | 0.33 |
| ▸ | TSSK2 | Q96PF2 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634574 | 1.00 | CHEK1 (0.36) | CHEK1GLSHDAC3HDAC2SCD | |
| SCHEMBL13164118 | 0.95 | CHEK1 (0.36) | CHEK1HDAC3HDAC2SCDSCD5 | |
| SCHEMBL13270439 | 0.95 | CHEK1 (0.36) | CHEK1HDAC3HDAC2SCDSCD5 | |
| SCHEMBL13634732 | 0.93 | CHEK1 (0.35) | CHEK1HDAC3HDAC2SCDSCD5 | |
| SCHEMBL13634669 | 0.89 | GLS (0.35) | CHEK1GLSSCDSCD5PARP1 | |
| SCHEMBL13634768 | 0.89 | GLS (0.35) | CHEK1GLSSCDSCD5PARP1 | |
| SCHEMBL13634906 | 0.88 | SCD (0.38) | CHEK1GLSSCDSCD5PARP1 | |
| SCHEMBL13634750 | 0.88 | IRAK4 (0.38) | GLSSCDSCD5IRAK4 | |
| SCHEMBL13634760 | 0.86 | GLS (0.40) | CHEK1GLSSCDSCD5 | |
| SCHEMBL13634751 | 0.86 | GLS (0.39) | CHEK1GLSSCDSCD5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |