Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634786 | 0.92 | IRAK4 (0.49) | IRAK4KMT2AOPRK1L3MBTL1 | |
| SCHEMBL13634936 | 0.90 | IRAK4 (0.41) | IRAK4KMT2AOPRK1 | |
| SCHEMBL13638897 | 0.90 | IRAK4 (0.47) | IRAK4KMT2AOPRK1L3MBTL1 | |
| SCHEMBL13634718 | 0.90 | IRAK4 (0.47) | IRAK4KMT2AOPRK1L3MBTL1 | |
| SCHEMBL13634879 | 0.89 | IRAK4 (0.46) | IRAK4KMT2AOPRK1 | |
| SCHEMBL13638768 | 0.88 | IRAK4 (0.46) | IRAK4KMT2AOPRK1L3MBTL1 | |
| SCHEMBL15888684 | 0.88 | IRAK4 (0.46) | IRAK4KMT2AOPRK1L3MBTL1 | |
| SCHEMBL2769203 | 0.88 | IRAK4 (0.39) | IRAK4KMT2AOPRK1 | |
| SCHEMBL13634699 | 0.85 | IRAK4 (0.50) | IRAK4 | |
| SCHEMBL13270719 | 0.84 | IRAK4 (0.41) | IRAK4KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |