Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.65 |
| ▸ | ALB | P02768 | 3/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12311708 | 1.00 | SIRT5 (0.65) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL18461328 | 0.91 | ALB (0.65) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL11887166 | 0.89 | KDM4E (0.56) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL10408291 | 0.89 | KDM4E (0.56) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL13446714 | 0.88 | SIRT5 (0.54) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL16285431 | 0.87 | SIRT5 (0.53) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL10130532 | 0.87 | SIRT5 (0.60) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL20414861 | 0.86 | KDM4E (0.52) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL20411608 | 0.86 | KDM4E (0.52) | SIRT5ALBSIRT6SIRT1FOLH1 | |
| SCHEMBL8106503 | 0.86 | KDM4E (0.52) | SIRT5ALBSIRT6SIRT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272154-A2 | SMALL MOLECULE COMPOUNDS | APERTOR PHARMACEUTICALS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20130244939-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130130979-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-8304391-B2 | Peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2012-11-06 | — | — | US | disclosed |
| US-20090227508-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-7528104-B2 | Peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2009-05-05 | — | — | US | disclosed |
| US-20070027074-A1 | Novel peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244939-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | SIRT5 3853/4885ALB 1115/4885SIRT6 3745/4885 |
| US-20090227508-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | SIRT5 3689/4885ALB 1060/4885SIRT6 3735/4885 |
| US-20130130979-A1 | PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | SIRT5 3689/4885ALB 1060/4885SIRT6 3735/4885 |
| US-20070027074-A1 | Novel peptides that bind to the erythropoietin receptor | EPOR, PROKR1, EDNRB | SIRT5 3853/4885ALB 1115/4885SIRT6 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.