Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL3983227 | 0.81 | SMN1; SMN2 (0.45) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| Methyl Alcohol SCHEMBL28005726 | 0.79 | SMN1; SMN2 (0.46) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| Ethane SCHEMBL323446 | 0.79 | SMN1; SMN2 (0.46) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL8373240 | 0.79 | POLB (0.50) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL361682 | 0.79 | — | — | |
| SCHEMBL1194 | 0.79 | — | — | |
| Ethane SCHEMBL28152828 | 0.77 | SMN1; SMN2 (0.45) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL7683711 | 0.77 | CXCR4 (0.52) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| SCHEMBL12958863 | 0.77 | KDM4E (0.50) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL7216847 | 0.77 | POLB (0.48) | CHRM5CHRM3SMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508523-B2 | Polymorphs of dasatinib and process for preparation thereof | TEVA PHARMA (IL) | 2019-04-17 | — | — | EP | disclosed |
| EP-2508523-B1 | Polymorphs of dasatinib and process for preparation thereof | TEVA PHARMA (IL) | 2016-02-17 | — | — | EP | disclosed |
| EP-2537847-A1 | Polymorphs of dasatinib and process for preparation thereof | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2012-12-26 | — | — | EP | disclosed |
| EP-2508523-A2 | Polymorphs of dasatinib and process for preparation thereof | Teva Pharmaceutical Industries Ltd. (IL) | 2012-10-10 | — | — | EP | disclosed |
| US-8067423-B2 | Polymorphs of dasatinib isopropyl alcohol and process for preparation thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-11-29 | — | — | US | disclosed |
| US-7973045-B2 | Anhydrous form of dasatinib and process for preparation thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2011-07-05 | — | — | US | disclosed |
| US-20100256158-A1 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2010-10-07 | — | — | US | disclosed |
| EP-2207777-A2 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | Teva Pharmaceutical Industries Ltd. (IL) | 2010-07-21 | — | — | EP | disclosed |
| US-20090118297-A1 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | ASSIA CHEMICAL INDUSTRIES LTD. (IL) | 2009-05-07 | — | — | US | disclosed |
| WO-2009053854-A2 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256158-A1 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | NRAS, SRC, TP53 | CHRM5 4637/4885CHRM3 4245/4885SMN1; SMN2 2398/4885 |
| US-20090118297-A1 | POLYMORPHS OF DASATINIB AND PROCESS FOR PREPARATION THEREOF | NRAS, SRC, TP53 | CHRM5 4637/4885CHRM3 4245/4885SMN1; SMN2 2398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.