Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | DRD3 | P35462 | 6/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16995031 | 0.99 | DRD2 (0.35) | DRD2DRD3FYNHTR1AHTR7 | |
| SCHEMBL13389234 | 0.99 | DRD2 (0.35) | DRD2DRD3FYNHTR1AHTR7 | |
| SCHEMBL4404563 | 0.99 | DRD2 (0.35) | DRD2DRD3FYNHTR1AHTR7 | |
| SCHEMBL13407519 | 0.99 | DRD2 (0.35) | DRD2DRD3FYNHTR1AHTR7 | |
| SCHEMBL16995028 | 0.91 | DRD2 (0.38) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL13407669 | 0.91 | DRD2 (0.38) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL13389237 | 0.91 | DRD2 (0.38) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL16995027 | 0.90 | DRD2 (0.37) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL13389639 | 0.90 | DRD2 (0.37) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL13389628 | 0.86 | TLR4 (0.30) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409441-B1 | INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY | MERCK PATENT GMBH (DE) | 2009-11-18 | — | — | EP | disclosed |