Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635052 | 0.91 | PTGS2 (0.38) | PTGS2ESR2 | |
| SCHEMBL14045665 | 0.90 | PTGS2 (0.37) | PTGS2MAPTESR2PTPN1 | |
| SCHEMBL13635220 | 0.89 | PTGS2 (0.38) | PTGS2ESR2 | |
| SCHEMBL13635600 | 0.83 | PTGS2 (0.35) | PTGS2ESR2 | |
| SCHEMBL13635257 | 0.82 | ESR2 (0.35) | PTGS2ESR2 | |
| SCHEMBL13624620 | 0.81 | PTGS2 (0.43) | PTGS2MAPTESR2 | |
| SCHEMBL14025307 | 0.81 | ESR2 (0.42) | PTGS2MAPTESR2 | |
| SCHEMBL14045664 | 0.81 | PTGS2 (0.41) | PTGS2ESR2 | |
| SCHEMBL13635256 | 0.80 | ESR2 (0.36) | PTGS2ESR2 | |
| SCHEMBL13632531 | 0.80 | PTGS2 (0.38) | PTGS2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622501-B2 | Nitric oxide releasing prodrugs of diaryl-2-(5H)-furanones as cyclooxygenase-2 inhibitors | MERCK FROSST CANADA & CO. (CA) | 2009-11-24 | — | — | US | disclosed |