SCHEMBL1363528

SCHEMBL1363528

C=CCC(=Cc1ccccc1)C(=O)OO

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 1/20 0.45
RECQL P46063 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MME P08473 2/20 0.39
AKR1C3 P42330 1/20 0.38
PAM P19021 1/20 0.37
AKR1C1 Q04828 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MAPT P10636 2/20 0.35
THRB P10828 1/20 0.35
NR1I2 O75469 1/20 0.35
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10555381 0.84 CYP3A4 (0.42) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL7064025 0.82 CYP3A4 (0.59) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL1717110 0.82 CYP3A4 (0.59) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL10972186 0.79 CYP3A4 (0.47) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL11768715 0.78 CYP3A4 (0.46) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL10972190 0.75 CYP3A4 (0.42) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL10968637 0.75 CYP3A4 (0.42) CYP3A4CYP2C9RECQLMEN1KMT2A
1,6-Hexanediol SCHEMBL31201193 0.71 CYP3A4 (0.46) CYP3A4CYP2C9RECQLMEN1KMT2A
SCHEMBL6047074 0.71 KDM4E (0.35) KDM4ETSHR
SCHEMBL27357828 0.71 ALDH1A1 (0.41) CYP3A4CYP2C9RECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067140-B2 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2011-11-29 US disclosed
US-20080182189-A1 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2008-07-31 US disclosed