Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635193 | 1.00 | CHRM3 (0.33) | CHRM3HSD11B1CYP2D6 | |
| SCHEMBL13767392 | 0.87 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL12856740 | 0.82 | SIGMAR1 (0.35) | — | |
| SCHEMBL12670478 | 0.80 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL14570095 | 0.80 | CYP1B1 (0.31) | — | |
| SCHEMBL19575551 | 0.79 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL10280031 | 0.79 | CHRM3 (0.33) | CHRM3 | |
| SCHEMBL13635367 | 0.79 | KDM4C (0.35) | — | |
| SCHEMBL13597356 | 0.78 | SLC18A3 (0.30) | — | |
| SCHEMBL13635190 | 0.78 | KMT2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1789402-B1 | 2-{-3-2-(PHENYL)-OXAZOL-4-YLMETHOXYMETHYL!-CYCLOHEXYLMETHOXY };-PROPIONIC ACID DERIVATIVES USED AS PPAR LIGANDES (PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS) FOR THE TREATMENT OF HYPERLIPIDAEMIE AND DIABETES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-18 | — | — | EP | disclosed |