Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387821 | 0.84 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4EGLN1 | |
| SCHEMBL383554 | 0.83 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4EGLN1 | |
| SCHEMBL385549 | 0.83 | S1PR1 (0.43) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL386909 | 0.74 | S1PR1 (0.44) | S1PR1S1PR3S1PR5S1PR4TSHR | |
| SCHEMBL386175 | 0.72 | S1PR1 (0.40) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL386800 | 0.72 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4EGLN1 | |
| SCHEMBL385741 | 0.71 | S1PR1 (0.55) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL386305 | 0.71 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL385736 | 0.71 | ALOX5 (0.36) | S1PR1S1PR3S1PR5EGLN1ALDH1A1 | |
| SCHEMBL385597 | 0.70 | S1PR1 (0.38) | S1PR1S1PR3S1PR5S1PR4EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | claimed |