Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 4/20 | 0.37 |
| ▸ | TTK | P33981 | 6/20 | 0.36 |
| ▸ | AURKA | O14965 | 5/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635246 | 0.69 | ITK (0.44) | MAPK10ITKTTKAURKAAURKB | |
| SCHEMBL27539189 | 0.62 | CLK2 (0.44) | ITKTTKAURKAAURKB | |
| SCHEMBL13635414 | 0.62 | MAPK10 (0.44) | MAPK10ITKPDPK1 | |
| SCHEMBL2868617 | 0.62 | MAPK10 (0.58) | MAPK10ITKTTKAURKAAURKB | |
| SCHEMBL2855817 | 0.61 | MAPK10 (0.58) | MAPK10ITKTTKAURKAAURKB | |
| SCHEMBL2864712 | 0.59 | ITK (0.56) | ITKTTKAURKAAURKB | |
| SCHEMBL2861747 | 0.58 | MAPK10 (0.78) | MAPK10ITKPDPK1 | |
| SCHEMBL2868361 | 0.58 | AURKA (0.50) | ITKTTKAURKAAURKB | |
| SCHEMBL2860663 | 0.57 | MAPK10 (0.67) | MAPK10ITKPDPK1 | |
| SCHEMBL2858445 | 0.57 | MAPK10 (0.67) | MAPK10ITKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-B1 | 1H-INDAZOLE COMPOUNDS INHIBITING JNK | EISAI R&D MAN CO LTD (JP) | 2009-11-25 | — | — | EP | disclosed |