Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539065 | 0.74 | POLB (0.62) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL2855841 | 0.71 | TTK (0.52) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL936411 | 0.70 | MEN1 (0.69) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL21468498 | 0.69 | MEN1 (0.65) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL2381404 | 0.65 | CDK9 (0.52) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL12237452 | 0.65 | DNMT1 (0.60) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL21499355 | 0.64 | MEN1 (0.58) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2422080 | 0.64 | POLB (0.57) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2331120 | 0.64 | DNMT1 (0.59) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL10817377 | 0.63 | MEN1 (0.66) | MEN1KMT2APOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-B1 | 1H-INDAZOLE COMPOUNDS INHIBITING JNK | EISAI R&D MAN CO LTD (JP) | 2009-11-25 | — | — | EP | disclosed |