Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378336 | 0.83 | L3MBTL1 (0.56) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2285212 | 0.80 | L3MBTL1 (0.74) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2280096 | 0.74 | L3MBTL1 (0.54) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL31238943 | 0.74 | L3MBTL1 (0.54) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL4390112 | 0.73 | L3MBTL1 (0.57) | L3MBTL1KDM4EGAAKMT2AHTT | |
| SCHEMBL24461480 | 0.69 | L3MBTL1 (0.49) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL28805883 | 0.69 | L3MBTL1 (0.54) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2280549 | 0.69 | L3MBTL1 (0.54) | L3MBTL1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL2279827 | 0.68 | SMN1; SMN2 (0.59) | L3MBTL1KDM4EKMT2AMEN1HTT | |
| SCHEMBL11785394 | 0.67 | GAA (0.58) | L3MBTL1KDM4EGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |