Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870047 | 0.82 | MEN1 (0.45) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL13198236 | 0.74 | NPC1 (0.40) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL14074919 | 0.72 | AURKA (0.49) | MEN1KMT2AALDH1A1HPGDCA1 | |
| SCHEMBL29610323 | 0.70 | P2RY14 (0.65) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL28356610 | 0.70 | P2RY14 (0.65) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL2861507 | 0.67 | TTK (0.47) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL2861505 | 0.67 | MAOB (0.48) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL2862233 | 0.66 | MEN1 (0.45) | MEN1KMT2AALDH1A1HPGDCA1 | |
| SCHEMBL13198297 | 0.64 | TOP2A (0.49) | MEN1KMT2AALDH1A1HPGDCYP1A2 | |
| SCHEMBL4341027 | 0.64 | KDM4E (0.40) | MEN1KMT2AALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380576-B1 | 1H-INDAZOLE COMPOUNDS INHIBITING JNK | EISAI R&D MAN CO LTD (JP) | 2009-11-25 | — | — | EP | disclosed |