SCHEMBL2870047

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861507	0.84	TTK (0.47)	MEN1KMT2AAURKAAURKBALDH1A1
	SCHEMBL2862233	0.82	MEN1 (0.45)	MEN1KMT2AAURKAAURKBALDH1A1
	SCHEMBL13198297	0.82	TOP2A (0.49)	MEN1KMT2AALDH1A1HPGDCYP1A2
	SCHEMBL13635944	0.82	MEN1 (0.45)	MEN1KMT2AALDH1A1HPGDCYP1A2
	SCHEMBL4341026	0.79	TSHR (0.41)	MEN1KMT2AALDH1A1HPGDCYP1A2
	SCHEMBL4341422	0.79	KDM4E (0.45)	KMT2ACYP1A2CYP2C19KDM4ESMN1; SMN2
	SCHEMBL4334435	0.78	KMT2A (0.47)	MEN1KMT2AALDH1A1HPGDKDM4E
	SCHEMBL4332111	0.74	SMN1; SMN2 (0.46)	MEN1KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL2872600	0.74	KDM4E (0.45)	MEN1KMT2AALDH1A1CA1CA5A
	SCHEMBL4341426	0.72	GAA (0.50)	MEN1KMT2AALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.