Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386869 | 0.84 | PTPN1 (0.62) | PTPN1 | |
| Trifluoroacetic Acid SCHEMBL3731700 | 0.77 | PTPN1 (0.57) | PTPN1 | |
| SCHEMBL4373578 | 0.71 | PTPN1 (0.72) | PTPN1 | |
| SCHEMBL4386872 | 0.68 | MCHR1 (0.36) | MCHR1PIM1PIM3PIM2 | |
| Trifluoroacetic Acid SCHEMBL3742365 | 0.67 | PTPN1 (0.65) | PTPN1 | |
| SCHEMBL4387061 | 0.67 | PTPN1 (0.74) | PTPN1 | |
| SCHEMBL17164061 | 0.67 | MCHR1 (0.49) | MCHR1CARM1PRMT1 | |
| SCHEMBL4380062 | 0.65 | PTPN1 (0.69) | PTPN1 | |
| SCHEMBL4384574 | 0.65 | PTPN1 (0.65) | PTPN1 | |
| SCHEMBL4377819 | 0.65 | PTPN1 (0.65) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910359-B1 | PYRIDO [2 , 3-D]PYRIMIDINE-2 , 4-DIAMINE COMPOUNDS AS PTPlB INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-18 | — | — | EP | disclosed |