Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14079 | 0.81 | PARP1 (0.35) | PARP1 | |
| SCHEMBL14850174 | 0.78 | PDGFRB (0.30) | — | |
| SCHEMBL13642 | 0.76 | ACKR3 (0.33) | PARP1 | |
| SCHEMBL17354123 | 0.75 | HDAC1 (0.39) | — | |
| SCHEMBL14176 | 0.75 | ROCK1 (0.40) | PARP1AURKB | |
| SCHEMBL14224 | 0.75 | HDAC1 (0.39) | LCK | |
| SCHEMBL17486524 | 0.75 | RORC (0.32) | PARP1AURKB | |
| SCHEMBL14853161 | 0.74 | PARP1 (0.31) | PARP1 | |
| SCHEMBL13897 | 0.74 | HDAC11 (0.34) | — | |
| SCHEMBL13751 | 0.74 | LYN (0.34) | AURKBLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |