Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948398 | 1.00 | USP30 (0.55) | USP30CA1CA2EPHX1ANO1 | |
| SCHEMBL25948405 | 1.00 | USP30 (0.55) | USP30CA1CA2EPHX1ANO1 | |
| SCHEMBL5118879 | 0.92 | EPHX1 (0.53) | USP30EPHX1HDAC4HDAC6PARP1 | |
| SCHEMBL18632877 | 0.92 | EPHX1 (0.53) | USP30EPHX1HDAC4HDAC6PARP1 | |
| SCHEMBL30505540 | 0.92 | EPHX1 (0.53) | USP30EPHX1HDAC4HDAC6PARP1 | |
| SCHEMBL18959262 | 0.87 | USP30 (0.53) | USP30CA1CA2EPHX1ANO1 | |
| SCHEMBL13636131 | 0.87 | USP30 (0.53) | USP30CA1CA2EPHX1ANO1 | |
| SCHEMBL19408900 | 0.87 | USP30 (0.53) | USP30CA1CA2EPHX1ANO1 | |
| SCHEMBL25245907 | 0.86 | NR1H2 (0.48) | USP30EPHX1FPR3FPR2 | |
| SCHEMBL16763600 | 0.85 | EPHX1 (0.53) | USP30CA1CA2EPHX1ANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099238-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-15 | — | — | WO | disclosed |
| EP-4552639-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-14 | — | — | EP | disclosed |
| WO-2009133389-A1 | METHODS OF PREPARING SUBSTITUTED HETEROCYCLES | ASTRAZENECA AB (SE) | 2009-11-05 | — | — | WO | disclosed |