Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123826 | 0.85 | TP53 (0.67) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL672374 | 0.85 | TP53 (0.67) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL3126342 | 0.85 | TP53 (0.67) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL3122491 | 0.85 | TP53 (0.67) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL3114962 | 0.85 | TP53 (0.67) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL23347771 | 0.79 | TP53 (0.44) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL2367335 | 0.79 | LMNA (0.45) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL23347575 | 0.78 | LMNA (0.49) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL16212082 | 0.78 | TP53 (0.55) | TP53LMNAHTTIDO1TDO2 | |
| SCHEMBL17120931 | 0.78 | LMNA (0.43) | TP53LMNAHTTIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304444-B2 | Pyrazole carboxylic acid amides useful as microbiocides | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-06 | — | — | US | disclosed |