Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190989 | 0.82 | MAOB (0.69) | ALOX5MAOB | |
| SCHEMBL5626572 | 0.82 | MAOB (0.69) | ALOX5MAOB | |
| Hydrochloric Acid SCHEMBL4384016 | 0.81 | MAOB (0.67) | ALOX5MAOB | |
| SCHEMBL14190987 | 0.80 | GPR183 (0.58) | — | |
| SCHEMBL2484236 | 0.79 | ALOX5 (0.60) | ALOX5MAOB | |
| Hydrochloric Acid SCHEMBL4378965 | 0.79 | GPR183 (0.57) | — | |
| Hydrochloric Acid SCHEMBL4378962 | 0.79 | GPR183 (0.57) | — | |
| SCHEMBL16382869 | 0.78 | MAOB (0.78) | ALOX5MAOB | |
| SCHEMBL1560606 | 0.78 | MAOB (0.78) | ALOX5MAOB | |
| SCHEMBL12334103 | 0.76 | MAOB (0.81) | ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | disclosed |