Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451622 | 0.96 | TDP1 (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL548112 | 0.87 | POLB (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL16620120 | 0.86 | TDP1 (0.55) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL15698361 | 0.85 | TDP1 (0.57) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL15385959 | 0.85 | HTT (0.65) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL454606 | 0.85 | POLB (0.67) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL13907647 | 0.84 | TDP1 (0.44) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL11997927 | 0.84 | HTT (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL22160227 | 0.84 | HTT (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL25784256 | 0.83 | TDP1 (0.56) | TDP1POLBAPEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2031000-B1 | Preparation method for a thermosetting polymer / thermoplastic polymer alloy type transparent material and its application in optics for the production of organic glasses | ESSILOR INT (FR) | 2009-11-25 | — | — | EP | disclosed |