Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451622 | 0.90 | TDP1 (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL548112 | 0.90 | POLB (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL15698361 | 0.88 | TDP1 (0.57) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL454606 | 0.87 | POLB (0.67) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL13636409 | 0.86 | TDP1 (0.52) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL25784256 | 0.86 | TDP1 (0.56) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL31040362 | 0.85 | TDP1 (0.51) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL381800 | 0.84 | TDP1 (0.57) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL29104794 | 0.83 | TDP1 (0.50) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL6561399 | 0.83 | POLB (0.52) | TDP1POLBAPEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160223904-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | TOYO GOSEI CO., LTD (JP) | 2016-08-04 | — | — | US | disclosed |
| US-20150241779-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150241779-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150241779-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-08-27 | — | — | US | disclosed |
| WO-2015049871-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | TOYO GOSEI CO., LTD. (JP) | 2015-04-09 | — | — | WO | disclosed |
| US-20150045255-A1 | Endometrial Phase or Endometrial Cancer Biomarkers | WALFISH, PAUL (CA) | 2015-02-12 | — | — | US | disclosed |