Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12977681 | 0.91 | RARB (0.52) | RARBRARARARGTP53HSD17B10 | |
| SCHEMBL10030220 | 0.89 | RARB (0.41) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL10030222 | 0.87 | RARB (0.38) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL12976836 | 0.87 | RARB (0.38) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL12976270 | 0.87 | RARB (0.38) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL24122286 | 0.86 | RARB (0.43) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL503169 | 0.86 | RARB (0.43) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL12976947 | 0.85 | RARB (0.37) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL10603849 | 0.85 | RARB (0.51) | RARBRARARARGMCL1TAAR1 | |
| SCHEMBL9512294 | 0.85 | RARB (0.51) | RARBRARARARGMCL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |