SCHEMBL9512294

SCHEMBL9512294

CCCc1ccc(-c2ccc(-c3ccc(CCC)cc3)c(F)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.51
RARA P10276 1/20 0.48
RARG P13631 1/20 0.48
MCL1 Q07820 1/20 0.45
TAAR1 Q96RJ0 1/20 0.42
KIF11 P52732 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOB P27338 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
CHKA P35790 1/20 0.39
ALOX5 P09917 1/20 0.39
MAPT P10636 1/20 0.39
GFER P55789 1/20 0.39
CYP17A1 P05093 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10603849 1.00 RARB (0.51) RARBRARARARGMCL1TAAR1
SCHEMBL20202978 0.98 RARB (0.50) RARBRARARARGMCL1TAAR1
SCHEMBL21741386 0.95 MAOB (0.49) RARBRARARARGMCL1TAAR1
SCHEMBL30232659 0.95 RARB (0.48) RARBRARARARGMCL1TAAR1
SCHEMBL11957382 0.95 RARB (0.48) RARBRARARARGMCL1TAAR1
SCHEMBL9999852 0.95 RARB (0.48) RARBRARARARGMCL1TAAR1
SCHEMBL18708400 0.95 MAOB (0.49) RARBRARARARGMCL1TAAR1
SCHEMBL17359399 0.93 RARB (0.57) RARBRARARARGMCL1HSD17B10
SCHEMBL12333085 0.93 RARB (0.47) RARBRARARARGMCL1TAAR1
SCHEMBL15725337 0.93 KIF11 (0.51) RARBRARARARGMCL1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20220389320-A1 POLYMER-STABILIZED LIQUID CRYSTAL COMPOSITION AND USE THEREOF BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD (CN) 2022-12-08 US disclosed
EP-3331965-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-01-05 EP disclosed
US-11162028-B2 Liquid crystal composition and application thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-11-02 US disclosed
US-20210017450-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-01-21 US disclosed
US-20200339884-A1 LIQUID CRYSTAL COMPOSITION AND USE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-10-29 US disclosed
US-20090131689-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2009-05-21 US disclosed
US-20090131689-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2009-05-21 US disclosed
US-7390538-B2 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2008-06-24 US disclosed
US-7390538-B2 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2008-06-24 US disclosed
WO-2007090787-A1 HYDROCYCLOPENTA[b]NAPHTHALENES NEMATEL GMBH & CO. KG (DE) 2007-08-16 WO disclosed
WO-2007085297-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2007-08-02 WO disclosed
US-20070001149-A1 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2007-01-04 US disclosed
US-20070001149-A1 Liquid-crystal medium containing monofluoroterphenyl compounds MERCK PATENT GMBH (DE) 2007-01-04 US disclosed
EP-0281611-B1 LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT MERCK PATENT GMBH (DE) 1993-11-24 EP disclosed
EP-0281611-A1 LIQUID CRYSTAL PHASES FOR ELECTRO-OPTIC DISPLAY ELEMENTS BASED ON THE ECB EFFECT. MERCK PATENT GMBH (DE) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 RARB 3196/4885RARA 3675/4885RARG 3904/4885
US-20090131689-A1 TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM CHRM1, C1S, CHRM2 RARB 1704/4885RARA 1145/4885RARG 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.