Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.76 |
| ▸ | PRSS1 | P07477 | 12/20 | 0.76 |
| ▸ | F2 | P00734 | 3/20 | 0.76 |
| ▸ | PLAT | P00750 | 1/20 | 0.66 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7897445 | 0.94 | F10 (0.68) | F10PRSS1F2PLATPLG | |
| SCHEMBL13636882 | 0.83 | F10 (0.52) | F10PRSS1F2PLAT | |
| SCHEMBL6641574 | 0.83 | F10 (0.52) | F10PRSS1F2PLAT | |
| SCHEMBL14509370 | 0.82 | F10 (0.87) | F10PRSS1F2PLATPLG | |
| Trifluoroacetic Acid SCHEMBL6644490 | 0.82 | F10 (0.67) | F10PRSS1F2PLATPLG | |
| SCHEMBL14509369 | 0.80 | F10 (0.81) | F10PRSS1F2PLATPLG | |
| SCHEMBL14509347 | 0.80 | F10 (0.82) | F10PRSS1F2PLATPLG | |
| SCHEMBL6639216 | 0.79 | F10 (0.79) | F10PRSS1F2PLAT | |
| Trifluoroacetic Acid SCHEMBL6643271 | 0.78 | F10 (0.73) | F10PRSS1F2PLAT | |
| SCHEMBL14509329 | 0.77 | F10 (0.77) | F10PRSS1F2PLATPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-B1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2009-11-25 | — | — | EP | disclosed |