Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636885 | 0.83 | F10 (0.76) | F10PRSS1F2PLAT | |
| SCHEMBL14534961 | 0.82 | F10 (0.61) | F10PRSS1F2PLATMAPT | |
| SCHEMBL6641574 | 0.68 | F10 (0.52) | F10PRSS1F2PLAT | |
| SCHEMBL6214905 | 0.67 | DRD2 (0.51) | MAPTCD274EGLN1 | |
| SCHEMBL3899304 | 0.67 | P4HB (0.51) | MAPTALDH1A1 | |
| SCHEMBL3899309 | 0.67 | P4HB (0.51) | MAPTALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6644490 | 0.66 | F10 (0.67) | F10PRSS1F2PLAT | |
| SCHEMBL14509370 | 0.65 | F10 (0.87) | F10PRSS1F2PLAT | |
| SCHEMBL6644814 | 0.65 | BRAF (0.42) | F10PRSS1F2HDAC1CD274 | |
| SCHEMBL14509347 | 0.64 | F10 (0.82) | F10PRSS1F2PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-B1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2009-11-25 | — | — | EP | disclosed |