Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 8/20 | 0.57 |
| ▸ | F2 | P00734 | 7/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | F10 | P00742 | 6/20 | 0.57 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637040 | 0.83 | F9 (0.51) | F7F2PRSS1F10HDAC1 | |
| SCHEMBL7149685 | 0.77 | F2 (0.93) | F7F2PRSS1F10MRGPRX1 | |
| SCHEMBL7149680 | 0.77 | F2 (0.93) | F7F2PRSS1F10MRGPRX1 | |
| SCHEMBL7149694 | 0.77 | F2 (0.93) | F7F2PRSS1F10MRGPRX1 | |
| SCHEMBL5564323 | 0.77 | RXFP1 (0.47) | F7F2PRSS1F10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8128699 | 0.77 | F7 (0.88) | F7F2PRSS1F10MRGPRX1 | |
| Hydrochloric Acid SCHEMBL8121789 | 0.77 | F7 (0.88) | F7F2PRSS1F10MRGPRX1 | |
| Hydrochloric Acid SCHEMBL7149307 | 0.77 | F7 (0.88) | F7F2PRSS1F10MRGPRX1 | |
| Acetic Acid SCHEMBL8124533 | 0.76 | F2 (0.90) | F7F2PRSS1F10MRGPRX1 | |
| Hydrochloric Acid SCHEMBL8120614 | 0.76 | F2 (0.66) | F7F2PRSS1F10MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339673-B1 | MALONAMIDE AND MALONAMIC ESTER DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY, THEIR PREPARATION AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-11 | — | — | EP | disclosed |