Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.35 |
| ▸ | TUBB | P07437 | 2/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27957867 | 0.77 | NPSR1 (0.42) | HPGDCYP1A2CYP2C19KDM4EALOX15 | |
| SCHEMBL27537457 | 0.72 | HPGD (0.45) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4774522 | 0.71 | HPGD (0.43) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4772581 | 0.70 | HPGD (0.42) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14145729 | 0.70 | HPGD (0.42) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30143994 | 0.70 | NPSR1 (0.45) | KDM4ENPSR1L3MBTL1CSNK2A1ALDH1A1 | |
| SCHEMBL13943352 | 0.70 | NPSR1 (0.45) | KDM4ENPSR1L3MBTL1CSNK2A1ALDH1A1 | |
| SCHEMBL28026566 | 0.69 | L3MBTL1 (0.57) | HPGDRAB9ASMN1; SMN2KDM4EALOX15 | |
| SCHEMBL4765220 | 0.69 | MAPK8 (0.45) | HPGDNPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14145705 | 0.69 | HPGD (0.41) | HPGDNPC1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606255-B1 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2009-11-11 | — | — | EP | disclosed |