Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21570073 | 0.87 | GPR119 (0.57) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL20570284 | 0.87 | GPR119 (0.57) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL74203 | 0.86 | GPR119 (0.67) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL25155272 | 0.86 | GPR119 (0.56) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL7334972 | 0.86 | GPR119 (0.56) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL31360100 | 0.86 | GPR119 (0.56) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL1809399 | 0.85 | GPR119 (0.57) | GPR119HRH3CHEK2PDE4APDE4B | |
| SCHEMBL30876497 | 0.85 | GPR119 (0.57) | GPR119HRH3CHEK2PDE4APDE4B | |
| SCHEMBL1134253 | 0.85 | GPR119 (0.55) | GPR119HRH3CHEK2ALDH1A1PDE4A | |
| SCHEMBL848331 | 0.84 | GPR119 (0.57) | GPR119HRH3CHEK2ALDH1A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140309-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |