Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580557 | 0.90 | PPARD (0.45) | PTGDR2THRBPPARAMEN1KMT2A | |
| SCHEMBL3578997 | 0.82 | P2RY14 (0.49) | THRBTP53HSD17B10NPSR1PPARA | |
| SCHEMBL13407815 | 0.81 | MAPT (0.52) | PTGDR2THRBTP53HSD17B10NPSR1 | |
| SCHEMBL13441795 | 0.80 | CETP (0.49) | PTGDR2THRBTP53HSD17B10NPSR1 | |
| SCHEMBL3589081 | 0.73 | PPARA (0.50) | TP53HSD17B10PPARAALDH1A1MEN1 | |
| SCHEMBL30835032 | 0.72 | SGMS2 (0.52) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL19831028 | 0.72 | SGMS2 (0.52) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL3462614 | 0.72 | MAPT (0.53) | THRBTP53HSD17B10ALDH1A1MEN1 | |
| SCHEMBL13523056 | 0.69 | KDM4E (0.49) | THRBTP53HSD17B10NPSR1PPARA | |
| SCHEMBL13523042 | 0.68 | MAPT (0.48) | THRBTP53HSD17B10PPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622491-B2 | Type 2 diabetes, atherosclerosis, cardiovascular disease, Syndrome X; carboxylic acids with dialkyldiether or thioether linking groups e.g. {4-[3-(2-Benzotriazol-2-yl-4-chloro-phenoxy)-propoxy]-phenyl}-acetic acid and {4-[3-(2-benzotriazol-2-yl-4-thiophen-2-yl-phenoxy)-propoxy]-phenyl}-acetic acid | METABOLEX INC. (US) | 2009-11-24 | — | — | US | disclosed |