Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929043 | 0.80 | RXRA (0.51) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL958307 | 0.80 | IDO1 (0.54) | RXRARXRBRXRGIDO1AR | |
| SCHEMBL25826312 | 0.79 | RXRA (0.50) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL549178 | 0.79 | RXRA (0.50) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL195493 | 0.79 | RXRA (0.50) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL24146520 | 0.79 | RXRA (0.50) | RXRARXRBRXRGARKIF11 | |
| SCHEMBL29507276 | 0.79 | RXRA (0.50) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL12069868 | 0.76 | FFAR1 (0.36) | RXRARXRBRXRG | |
| SCHEMBL24146756 | 0.75 | RXRA (0.45) | RXRARXRBRXRGIDO1POLQ | |
| SCHEMBL16121256 | 0.73 | RXRA (0.59) | RXRARXRBRXRGPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622605-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-11-24 | — | — | US | disclosed |