Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 8/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212930 | 0.85 | DYRK3 (0.33) | MEN1KMT2ADYRK3DYRK1ADYRK2 | |
| SCHEMBL2918014 | 0.84 | RPA1 (0.43) | MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL2918833 | 0.82 | JMJD6 (0.44) | MEN1KMT2APOLBJMJD6GAA | |
| SCHEMBL2915598 | 0.79 | MALT1 (0.42) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL2910906 | 0.75 | CFTR (0.45) | MEN1KMT2APOLBPIK3CDSMN1; SMN2 | |
| SCHEMBL2920424 | 0.72 | RPA1 (0.46) | MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL14353634 | 0.71 | LMNA (0.63) | MEN1KMT2AOXTRCHRNB2CHRNA4 | |
| SCHEMBL13212903 | 0.70 | CCR1 (0.41) | MEN1KMT2AOXTRAVPR1AOGA | |
| SCHEMBL2910909 | 0.69 | JMJD6 (0.47) | MEN1KMT2APOLBJMJD6GAA | |
| SCHEMBL2909942 | 0.69 | RPA1 (0.51) | MEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |