Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sumacetamol SCHEMBL5185790 | 0.90 | GAA (0.55) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| Sumacetamol SCHEMBL1134071 | 0.90 | GAA (0.55) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL13637985 | 0.84 | KMT2A (0.54) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133955 | 0.83 | KMT2A (0.53) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133853 | 0.83 | KMT2A (0.53) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133956 | 0.83 | EPHX2 (0.52) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133954 | 0.83 | EPHX2 (0.52) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133950 | 0.80 | KMT2A (0.55) | KMT2AMEN1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL1133962 | 0.77 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2HSD17B10NPSR1 | |
| SCHEMBL18211946 | 0.76 | GAA (0.54) | KMT2AGAAHSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143299-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | NEUROGESX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |