Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133955 | 0.85 | KMT2A (0.53) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL1133853 | 0.85 | KMT2A (0.53) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| Sumacetamol SCHEMBL1134071 | 0.84 | GAA (0.55) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL13637924 | 0.84 | KMT2A (0.51) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| Sumacetamol SCHEMBL5185790 | 0.84 | GAA (0.55) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL1133956 | 0.78 | EPHX2 (0.52) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL1133954 | 0.78 | EPHX2 (0.52) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL1133950 | 0.77 | KMT2A (0.55) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL18486770 | 0.75 | KMT2A (0.53) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL1133856 | 0.72 | KMT2A (0.57) | KMT2AMEN1NPSR1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143299-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | NEUROGESX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |