Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923038 | 1.00 | LMNA (0.59) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL10461156 | 1.00 | LMNA (0.59) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL6058989 | 1.00 | LMNA (0.59) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL8609071 | 0.91 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL19000301 | 0.91 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL12552441 | 0.91 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16605707 | 0.91 | LMNA (0.65) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL12240960 | 0.88 | TDP1 (0.67) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16074668 | 0.83 | TDP1 (0.53) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL14346962 | 0.83 | TDP1 (0.53) | LMNAL3MBTL1TDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689789-B1 | NOVEL CYCLODEXTRIN DIMERS AND DERIVATIVES THEREOF, METHODS FOR PREPARING THEM AND THEIR USE, IN PARTICULAR, FOR SOLUBILIZING PHARMACOLOGICALLY ACTIVE SUBSTANCES | CENTRE NAT RECH SCIENT (FR) | 2009-11-11 | — | — | EP | disclosed |