Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638424 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL21629528 | 0.78 | ALDH1A1 (0.81) | ALDH1A1KDM4EMAPTHPGDLMNA | |
| SCHEMBL17403186 | 0.77 | KDM4E (0.76) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL17269967 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL14394953 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL14027239 | 0.74 | KDM4E (0.63) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL18661752 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL14028419 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL20364004 | 0.73 | ALDH1A1 (0.77) | ALDH1A1KDM4EMAPTHPGDPKM | |
| SCHEMBL21629627 | 0.73 | ALDH1A1 (0.83) | ALDH1A1KDM4EMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622499-B2 | β-Benzyloxyaspartate derivatives with photosensitive groups | SUNTORY HOLDINGS LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20070158175-A1 | (2S,3S)-3-Benzyloxy-N-[7-(carboxymethoxy) coumarin-4-ylmethoxy]carbonylaspartate; upon photoirradiation can produce compounds exhibiting a function of suppressing the glutamate uptake activity of L-glutamate transporters; use in treatment of neurological disorders and neurodegenerative conditions | SUNTORY HOLDINGS LIMITED (JP) | 2007-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070158175-A1 | (2S,3S)-3-Benzyloxy-N-[7-(carboxymethoxy) coumarin-4-ylmethoxy]carbonylaspartate; upon photoirradiation can produce compounds exhibiting a function of suppressing the glutamate uptake activity of L-glutamate transporters; use in treatment of neurological disorders and neurodegenerative conditions | SLC1A1, SLC1A2, SLC1A3 | ALDH1A1 263/4885KDM4E 2999/4885MAPT 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.