Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638527 | 0.88 | P2RY12 (0.45) | P2RY12TP53HTR3ARXFP1AKR1C3 | |
| SCHEMBL6017209 | 0.82 | P2RY12 (0.54) | P2RY12TP53HTR3ARXFP1MAPT | |
| SCHEMBL9922414 | 0.82 | P2RY12 (0.58) | P2RY12TP53HTR3ARXFP1MAPT | |
| SCHEMBL12161684 | 0.80 | P2RY12 (0.56) | P2RY12TP53MAPT | |
| SCHEMBL17715382 | 0.80 | P2RY12 (0.49) | P2RY12TP53HTR3ARXFP1PPARG | |
| SCHEMBL13638520 | 0.79 | P2RY12 (0.47) | P2RY12TP53RXFP1MAPT | |
| SCHEMBL13638523 | 0.79 | P2RY12 (0.55) | P2RY12TP53HTR3ARXFP1MAPT | |
| SCHEMBL9923005 | 0.77 | P2RY12 (0.54) | P2RY12TP53PPARGMAPT | |
| SCHEMBL9922413 | 0.74 | P2RY12 (0.59) | P2RY12TP53HTR3ARXFP1MAPT | |
| SCHEMBL4412669 | 0.74 | P2RY12 (0.70) | P2RY12TP53RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |